Two recently published studies from National Institutes of Health highlight the role that IgG foods can have on migraines.While the researchers didn't give the elimination of food allergens enough time to work, (only 2 weeks), they still saw nearly a 30% reduction in migraines.
If the individuals had been able avoid the relevant foods for 2 months, I have no doubt that the results would have been much better.
While we are only going to highlight one of the studies, both are available by following the links at the end of the post.
From NIH.gov:
Diet restriction in migraine, based on IgG against foods: a clinical double-blind, randomised, cross-over trial.
INTRODUCTION
It is well-known that specific foods trigger migraine attacks in some patients. We aimed to investigate the effect of diet restriction, based on IgG antibodies against food antigens on the course of migraine attacks in this randomised, double blind, cross-over, headache-diary based trial on 30 patients diagnosed with migraine without aura.
METHODS
Following a 6-week baseline, IgG antibodies against 266 food antigens were detected by ELISA. Then, the patients were randomised to a 6-week diet either excluding or including specific foods with raised IgG antibodies, individually. Following a 2-week diet-free interval after the first diet period, the same patients were given the opposite 6-week diet (provocation diet following elimination diet or vice versa). Patients and their physicians were blinded to IgG test results and the type of diet (provocation or elimination). Primary parameters were number of headache days and migraine attack count. Of 30 patients, 28 were female and 2 were male, aged 19-52 years (mean, 35 +/- 10 years).
RESULTS
The average count of reactions with abnormally high titre was 24 +/- 11 against 266 foods. Compared to baseline, there was a statistically significant reduction in the number of headache days (from 10.5 +/- 4.4 to 7.5 +/- 3.7; P < style="color: rgb(0, 0, 153); font-weight: bold;">
CONCLUSION
This is the first randomised, cross-over study in migraineurs, showing that diet restriction based on IgG antibodies is an effective strategy in reducing the frequency of migraine attacks.
PMID: 20647174 [PubMed - indexed for MEDLINE]PMCID: PMC2899772Free PMC Article
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Links
Case #1
Diet restriction in migraine, based on IgG against foods: a clinical double-blind, randomised, cross-over trial.
Alpay K, Ertas M, Orhan EK, Ustay DK, Lieners C, Baykan B.
Cephalalgia. 2010 Jul;30(7):829-37. Epub 2010 Mar 10.
PMID: 20647174 [PubMed - indexed for MEDLINE]
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Case #2
IgG-mediated allergy: a new mechanism for migraine attacks?
Pascual J, Oterino A.
Cephalalgia. 2010 Jul;30(7):777-9. Epub 2010 Mar 26. No abstract available.
PMID: 20647169 [PubMed - indexed for MEDLINE]
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Image thanks to mypatrick4lfe on Photobucket
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